Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06260111

Photobiomodulation for Oral Mucositis and Functional Impairments During Hematopoietic Stem Cell Transplantation

Led by Universidad del Desarrollo · Updated on 2024-07-11

30

Participants Needed

1

Research Sites

72 weeks

Total Duration

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Sponsors

U

Universidad del Desarrollo

Lead Sponsor

A

Agencia Nacional de Investigación y Desarrollo

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to test the efficacy of laser photobiomodulation in adult hematologic cancer patients undergoing hematopoietic stem cell transplantation (HSCT). The main questions it aims to answer are: • Is photobiomodulation with laser in the oral cavity, compared to standard care, effective in preventing oral mucositis and functional impairments in adult patients receiving HSCT? • What is the level of patient´s acceptability of photobiomodulation with laser in the oral cavity during HSCT? Participants once a day will receive photobiomodulation (diode laser device) in their oral cavity from the first day of transplantation conditioning until third day post-transplant. Researchers will compare with usual care to see if photobiomodulation helps preventing oral mucositis and functional impairment.

CONDITIONS

Official Title

Photobiomodulation for Oral Mucositis and Functional Impairments During Hematopoietic Stem Cell Transplantation

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults over 18 years of age with hematological neoplasms who require medical indication of an HSCT according to the Transplant Committee at Clinica D�
Not Eligible

You will not qualify if you...

  • Observed cognitive deficit
  • Patients who do not meet the criteria of clinical stability, progression of the disease, and that do not fulfill requirement of the National Hematopoietic Stem Cell Transplantation Program.
  • Participants with an oral infection from any type of Candida prior to HSCT.

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Trial Site Locations

Total: 1 location

1

Clinica Dávila

Santiago, Santiago Metropolitan, Chile, 8431657

Actively Recruiting

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Research Team

C

Cinara Sacomori, Ph.D.

CONTACT

T

Tomás Lopez, MScC.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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