Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05106608

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

Led by Universidad de Granada · Updated on 2026-01-05

60

Participants Needed

1

Research Sites

228 weeks

Total Duration

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AI-Summary

What this Trial Is About

The Photobiomodulation therapy could have positive effects on quality of life and oral health in head and neck cancer survivors post-radiotherapy. The improvement in quality of life will be maintained after a follow-up period.

CONDITIONS

Official Title

Photobiomodulation Therapy Plus M-health in Head and Neck Cancer Patients: LAXER Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men or women aged 18 years or older diagnosed with head and neck cancer
  • Chronic xerostomia
  • Received radiotherapy to the parotid, submandibular, and/or sublingual salivary glands
  • Grade 3 oral dryness according to Common Terminology Criteria for Adverse Events version 5.0 (CTCAE)
  • Completed medical treatment and currently in complete remission
  • Medical clearance to participate in the study
  • At least one month and no more than 36 months since the end of radiotherapy
  • No history of drugs, devices, or products to prevent or treat xerostomia prior to study or no change in their use for two months before inclusion
  • Able to access mobile applications or living with someone who can
Not Eligible

You will not qualify if you...

  • Presence of metastases
  • Karnofsky Performance Status Scale score less than 60
  • Contraindications for PBM therapy (e.g., cardiac arrhythmias, pacemakers, photosensitivity, photosensitizing drugs, pregnancy)
  • Other comorbidities such as diabetes or polypharmacy
  • Withdrawal of consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Faculty of Health Sciences

Granada, Granada, Spain, 18070

Actively Recruiting

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Research Team

N

Noelia Galiano-Castillo, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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