Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
MALE
Healthy Volunteers
NCT06380179

Photomedicine Project 14: PBMT for Performance Enhancement in SOF

Led by Musculoskeletal Injury Rehabilitation Research for Operational Readiness (MIRROR) · Updated on 2025-07-03

116

Participants Needed

1

Research Sites

44 weeks

Total Duration

On this page

Sponsors

M

Musculoskeletal Injury Rehabilitation Research for Operational Readiness (MIRROR)

Lead Sponsor

U

Uniformed Services University (USU) of the Health Sciences

Collaborating Sponsor

AI-Summary

What this Trial Is About

Special Operations Forces (SOF) train continually to maintain peak performance. Thus, they are nearly always in a state of recovery, and in need of noninvasive therapies to address the taxing workload. Photobiomodulation therapy (PBMT) is a noninvasive treatment where a low-level laser is applied to the body to enhance healing, recovery, and performance. Army Tactical Human Optimization Rapid Rehabilitation and Reconditioning (THOR3) provides a consistent avenue for implementation of PBMT as a modality. Studies in athletes have shown performance and recovery benefits with pre-and post-workout focal application of PBMT. While there is less evidence on the potential cognitive/behavioral effects of a systematic application of PBMT, self-reported fatigue has also been found to be significantly lower in groups with focal PBMT application as compared to placebo. Further, PBMT research in healthy military tactical athletes is limited. PBMT may be a promising tool for enhancing physical performance by accelerating musculoskeletal and psychological recovery in the SOF population. The investigators aim to study the physiologic and behavioral effects of PBMT application post-exercise on performance in SOF Operators. The Intent: The investigators propose to conduct a single-blinded randomized-control trial with sham control to investigate the effectiveness of providing PBMT post physical training in a SOF population. The specific aims of this study are to: 1. Analyze and describe the physiologic effects, if any, of PBMT application post-exercise in Special Forces Operators undergoing coach-led training. 2. Analyze and describe the behavioral effects, if any, of PBMT application post-exercise in Special Forces Operators undergoing coach-led training. 3. Evaluate the overall clinical utility of focal PBMT subsequent to physical training in a US Army SOF, tactical athlete population.

CONDITIONS

Official Title

Photomedicine Project 14: PBMT for Performance Enhancement in SOF

Who Can Participate

Age: 18Years - 45Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Active-Duty Special Forces Personnel (18-series)
  • Able to read and understand English for consent
  • Able to commit to study intervention and follow-up
  • Able to participate in THOR3 coach-led training without restrictions
Not Eligible

You will not qualify if you...

  • Female
  • Obese with body fat over 25%
  • Cardiovascular disease
  • Use of certain medications such as statins, diuretics, hypertensive agents
  • Tattoo in the treatment area (quadriceps)
  • Diagnosis of porphyria or photosensitive eczema
  • Current use of medications causing sensitivity to heat or light (e.g., amiodarone, chlorpromazine, doxycycline, hydrochlorothiazide, nalidixic acid, naproxen, piroxicam, tetracycline, thioridazine, voriconazole)
  • Use of pacemaker or underlying cardiac disease
  • Diagnosed autoimmune diseases
  • Albinism
  • Peripheral neuropathy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Joint Base Lewis-McChord

Joint Base Lewis McChord, Washington, United States, 98433

Actively Recruiting

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Research Team

B

Bradley H Cornell, DPT

CONTACT

N

Nicholas R Hughes, DPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Photomedicine Project 14: PBMT for Performance Enhancement in SOF | DecenTrialz