Actively Recruiting
Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies
Led by University Hospital, Strasbourg, France · Updated on 2025-08-08
726
Participants Needed
1
Research Sites
366 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The light has visual and non-visual effects on organism and can act on the behavior, the mood, the cognition and the sleep. These effects are mediated by "classical" retina photoreceptors which allow vision (rods, cones) but also melanopsin cells. The non-visual effects of light seems to be altered in many neurological, psychiatric or ophtalmological conditions but their exact role in the pathogenesis remains poorly understand. The purpose of the study is to increase our knowledge of the non-visual effects of light and establish new therapeutic applications
CONDITIONS
Official Title
Photomotor Reflex to Evaluate the Role of the Non-visual Effects of Light in Neurological, Psychiatric and Ophthalmological Pathologies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Man or woman
- Aged 18 years or older
- Subject having signed a free and informed consent
- Subject affiliated to a social protection scheme
- Subjects with primary sleep-wake disorder
- Subjects presenting a neurological pathology with disorder of the controls of the wake and the sleep
- Subjects presenting a psychiatric pathology with disorder of the controls of the wake and the sleep
- Subjects presenting an ophthalmological pathology with possible alteration of the photoreception and/or phototransduction
- Subjects with photosensitivity with regulation disorder of sleep and wake
- Healthy subjects
You will not qualify if you...
- Age-Related Macular Degeneration (AMD) and all maculopathies (retinopathies pigmentosa, macular involvement of diabetes)
- Cataract with significant vision loss <5/10
- Chorioretinal neovascularization
- Subject in exclusion period determined by previous or current study
- Impossibility to give the subject information enlightened (subject in emergency situation, difficulties of understanding the subject, ...)
- Subject under the protection of justice
- Subject under guardianship or curatorship
- Pregnancy / Breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital, Strasbourg, France
Strasbourg, France, 67000
Actively Recruiting
Research Team
B
Bourgin Patrice, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
6
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