Ultrasound-Guided Phrenic Nerve Block to Reduce Neck Pain in Adults A Phase 4 Randomized Controlled Trial for Patients with Peridiaphragmatic Disorders

What this Trial Is About

Neck pain often occurs alongside conditions affecting organs near the diaphragm, which share nerve connections through the phrenic nerve. This trial evaluates whether blocking the phrenic nerve can reduce sensitivity and improve neck pain symptoms in people without neurological, traumatic, or infectious causes of pain. The study is a randomized controlled trial aiming to better understand the role of visceral organ involvement in neck pain and to identify potential targeted treatments. Participants will be randomly assigned to one of two groups. The experimental group will receive an ultrasound-guided injection of local anesthetics lidocaine and bupivacaine around the phrenic nerve to block nerve signals. The control group will receive a similar procedure with a saline solution as a placebo. The intervention involves a single session with follow-up assessments over one week to monitor changes. During the study, participants will undergo several evaluations including pain threshold measurements using algometry, range of motion tests, visual pain scales, and neck disability questionnaires. These assessments will be done before the procedure and at multiple points up to seven days afterward. The researchers will track changes in pain sensitivity and functional outcomes to determine the effects of phrenic nerve blockade on neck pain.

Phrenic Nerve Infiltration in Neck Pain