Actively Recruiting

Phase Not Applicable
Age: 5Years - 17Years
All Genders
NCT07325305

Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes

Led by Murdoch Childrens Research Institute · Updated on 2026-04-13

60

Participants Needed

1

Research Sites

135 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a small trial testing out a new approach before doing a bigger study. Researchers are observing a group of children/adolescents (ages 5-17) with acute lymphoblastic leukemia (ALL) and testing a physical activity and exercise program on a group of them who after 5 weeks of treatment show signs of weakness or frailty. Kids who are NOT losing muscle aren't part of the exercise trial - they're just monitored over time to see how they do. The goal: To see if an exercise program helps kids who are getting weaker from acute lymphoblastic leukemia treatment build back/maintain their strength, compared to kids who don't do the extra intervention. The study will also look at if this way of measuring muscle weakness works well for kids with cancer.

CONDITIONS

Official Title

Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes

Who Can Participate

Age: 5Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 5-17 years at the time of consent
  • New diagnosis of acute lymphoblastic leukaemia less than 7 days
  • Planned to receive cancer treatment at the trial site for the duration of the study
  • Has a legally acceptable representative who can understand English and provide consent
  • Have a family electronic device that can be linked with the Fitbit activity tracker
Not Eligible

You will not qualify if you...

  • none

AI-Screening

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Trial Site Locations

Total: 1 location

1

Royal Children's Hospital

Melbourne, Victoria, Australia, 3052

Actively Recruiting

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Research Team

S

Sarah Grimshaw, PhD Physiotherapy

CONTACT

E

Ella Thorburn, Bachelor of Physiotherapy(hon)

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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