Actively Recruiting
Physical Activity and Insulin Sensitivity Dynamics
Led by University of Copenhagen · Updated on 2025-12-02
8
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study investigates the role of one single bout of exercise in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. Furthermore, the study is aiming to elucidate the temporal development in insulin signaling, at the early timepoints of insulin stimulation that may be responsible for the enhanced muscle insulin sensitivity. This will be investigated in young healthy males subjected to a one-legged knee-extensor exercise followed by a hyperinsulinemic-euglycemic clamp, a setup known to enhance muscle insulin sensitivity.
CONDITIONS
Official Title
Physical Activity and Insulin Sensitivity Dynamics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy individuals with no known diseases
- No use of medication
- Non-smokers
- Male gender
- Aged between 22 and 35 years
- Fitness level (maximal oxygen uptake) between 30 and 50 mL O2/min/kg
- Body mass index (BMI) between 28 and 35
You will not qualify if you...
- Female gender
- Failing to meet all inclusion criteria
- Physical activity exceeding 6 hours per week
- Acute illness within 2 weeks before the study
- Use of recreational drugs within 2 weeks before the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Copenhagen, August Krogh Section for Human and Molecular Physiology
Copenhagen, Denmark, 2100
Actively Recruiting
Research Team
J
Jørgen FP Wojtaszewski, Professor
CONTACT
N
Nicolai S Henriksen, MSc
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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