Actively Recruiting
Physical Exercise for Cognitive Rehabilitation of Patients With Bipolar Affective Disorder
Led by Beny Lafer · Updated on 2024-08-19
72
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to evaluate the impact of Physical Exercise (PE), as an adjuvant treatment, on the cognition of patients diagnosed with Bipolar Disorder who present cognitive impairments, as well as its impact on quality of life and functionality and its association with physiological variables. Our specific goals are: 1. Evaluate the effect of PE on the neuropsychological functions of attention, memory, verbal fluency, executive function and processing speed in patients diagnosed with BD who present cognitive impairments in these domains. 2. To evaluate the effect of PE on the quality of life and functionality of patients diagnosed with BD, as well as possible associations with cognitive functions. 3. To evaluate possible correlations between physiological variables, such as cardiorespiratory indices, strength and body composition, and improvements in cognitive functions, quality of life and functionality.
CONDITIONS
Official Title
Physical Exercise for Cognitive Rehabilitation of Patients With Bipolar Affective Disorder
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Bipolar Disorder I or II according to DSM-5
- Age between 18 and 55 years old
- Completed primary education
- Euthymic mood state (YMRS < 8 and MADRS < 12)
- Cognitive impairments present (COBRA > 14 and SCIP < 75)
- Estimated IQ of 80 or higher
- No changes in medication during the last month
- No regular physical exercise in the past six months
- Signed informed consent (TCLE)
You will not qualify if you...
- Presence of organic mental disorder
- Body Mass Index (BMI) over 40
- Alcohol or drug abuse in the last 6 months
- Use of benzodiazepines or beta-blockers in the last month
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Gabriel Okawa Belizario
São Paulo, São Paulo, Brazil, 05403-903
Actively Recruiting
Research Team
G
Gabriel Okawa Belizario
CONTACT
B
Beny Lafer, M.D, Ph.D
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SCREENING
Number of Arms
2
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