Actively Recruiting

Age: 18Years +
All Genders
NCT07032870

Physical Therapist Inter-Rater Reliability in Neuro-Muscle Ultrasound in Critically Ill Patients

Led by University of Chile · Updated on 2025-07-25

37

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

Sponsors

U

University of Chile

Lead Sponsor

C

Clinica Indisa

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to evaluate the feasibility and inter-rater reliability of muscle and peripheral nerve ultrasound for the early detection of ICU-acquired weakness (ICU-AW) in critically ill patients. The main questions it aims to answer are: Can ICU physical therapists consistently measure muscle and nerve ultrasound variables such as muscle thickness, cross-sectional area, pennation angle, and echogenicity in critically ill patients? Do clinical scales (MRC-SS and FSS-ICU) show inter-evaluator agreement and correlate with ultrasound findings? Participants are adult ICU patients at Clínica INDISA who are undergoing routine neuromuscular assessments by trained physical therapists. Each patient will be evaluated by three independent raters using ultrasound and standardized clinical scales. Data will be collected and analyzed to determine inter-rater reliability and correlations between clinical and imaging findings.

CONDITIONS

Official Title

Physical Therapist Inter-Rater Reliability in Neuro-Muscle Ultrasound in Critically Ill Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients (18 years or older) admitted to the Adult Intensive Care Unit (ICU) of Clínica INDISA
  • Conscious and clinically stable at the time of assessment
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Known allergy to ultrasound gel
  • Body mass index (BMI) 30 kg/m² or higher
  • Pre-existing neuromuscular disease
  • Receiving continuous renal replacement therapy or have severe hepatic coagulopathy
  • Platelet count less than 20,000/µL
  • Lower limb amputation or recent fractures
  • Ongoing chemotherapy or immunosuppressive treatment with corticosteroids
  • Epileptic status or pregnancy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Clínica INDISA

Santiago, Metropolitan Region, Chile, 7500912

Actively Recruiting

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Research Team

Ó

Óscar L Arellano, MSc. PhD Candidate

CONTACT

B

Benito J Arévalo, MSc.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Physical Therapist Inter-Rater Reliability in Neuro-Muscle Ultrasound in Critically Ill Patients | DecenTrialz