Actively Recruiting

Phase Not Applicable
Age: 18Years - 100Years
All Genders
NCT06578156

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Led by University of Miami · Updated on 2026-04-03

30

Participants Needed

1

Research Sites

159 weeks

Total Duration

On this page

Sponsors

U

University of Miami

Lead Sponsor

A

American Thoracic Society

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to assess whether to describe the effects of the administration of nasal high flow (NHF) at 70 liters per minute (L/min) in a 6-Minute Walk Test (6-MWT) among Chronic Obstructive Pulmonary Disease (COPD) patients and to characterize the association between self-reported dyspnea with and without NHF at 70 L/min following a 6-MWT.

CONDITIONS

Official Title

Physiologic Effects of Nasal High Flow on Exercise Tolerance in COPD

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Able to consent
  • Age 18 years or older
  • Diagnosis of COPD
  • Ability to ambulate without assistance
  • Use of low-flow nasal cannula 4 L/min or no supplemental oxygen at all
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Being on bedrest
  • Inability to consent or cooperate with the study
  • Using of > 4 L/min of supplemental oxygen or requiring non-invasive ventilation during the daytime
  • Hemodynamic instability (resting heart rate > 130/minute, systolic blood pressure 4 90 mmHg or 6 180 mmHg)
  • Metal implants in the thoracic regions (pacemakers, Automatic Implantable Cardioverter Defibrillator (AICD), plates, screws, rods, and disc replacements)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Miami

Miami, Florida, United States, 33136

Actively Recruiting

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Research Team

S

Saramaria Afanador Castiblanco, M.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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