Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06696638

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

Led by XiaoJing Zou,MD · Updated on 2025-01-06

26

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

X

XiaoJing Zou,MD

Lead Sponsor

U

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study aims to investigate the effects of EIT-guided and Pplat-guided Phigh settings on regional ventilation and perfusion in ARDS patients during APRV, while also examining the impact of different Phigh settings on gas exchange, respiratory mechanics, and hemodynamics.

CONDITIONS

Official Title

Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with ARDS according to the 2023 global new definition of ARDS.
  • Age 18 years or older.
Not Eligible

You will not qualify if you...

  • Severe chronic obstructive pulmonary disease, severe asthma, pulmonary bullae, pneumothorax, subcutaneous emphysema, mediastinal emphysema, or similar conditions.
  • Contraindications for EIT such as chest wound dressing, pacemaker implantation, or defibrillator use.
  • Pulmonary interstitial disease.
  • Uncorrected shock of various types.
  • Intracranial hypertension.
  • Pregnant and postpartum women.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Wuhan Union hospital

Wuhan, Hubei, China, 237000

Actively Recruiting

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Research Team

J

jing Xiao Zou

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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Physiological Effects of Lung Impedance Tomography-Guided and Plat Pressure-Guided Phigh During APRV in Patients With ARDS | DecenTrialz