Actively Recruiting

Phase Not Applicable
Age: 18Months +
All Genders
Healthy Volunteers
NCT07152652

Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect

Led by University of Helsinki · Updated on 2025-09-29

148

Participants Needed

1

Research Sites

168 weeks

Total Duration

On this page

Sponsors

U

University of Helsinki

Lead Sponsor

S

Strategic Research Council, Finland

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this trial is to learn if the Groups 4 Health (G4H) intervention is effective in supporting student well-being at the University of Helsinki. It will also learn about the factors that may influence the efficacy of the intervention (such as facilitators characteristics, stress physiology and changes in gene expression). The main questions it aims to answer are: 1. Is the G4H intervention effective and cost-effective in supporting student well-being? 2. To what extent participants' physiological, hormonal, or molecular characteristics mediate the therapeutic effect of the G4H 3. To what extent participants' genotype moderates the effect of the G4H 4. To what extent facilitators' characteristics mediate or moderate the effect of the G4H Data is collected from both the intervention participants and the facilitators. The G4H facilitators will: * Facilitate the G4H intervention. * Fill in questionnaires and provide physiological and molecular measurements before, during, and after the G4H intervention. The G4H participants will: * Participate in the G4H intervention. * Fill in questionnaires and provide physiological, hormonal and molecular measurements before, during, and after the G4H intervention.

CONDITIONS

Official Title

Physiological, Hormonal, and DNA-based Mechanisms of Psychosocial Stress and Therapeutic Effect

Who Can Participate

Age: 18Months +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult (age 18 and above)
  • Currently a student at the University of Helsinki, Finland
  • Able to speak and read Finnish, Swedish, or English
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Helsinki

Helsinki, Uusimaa, Finland, 00014

Actively Recruiting

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Research Team

J

Jari Lahti, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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