Actively Recruiting
Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval
Led by Quovadis Associazione · Updated on 2025-05-11
640
Participants Needed
1
Research Sites
331 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A multicenter, prospective, randomized study in a 1:1 ratio, single-blind with double-blind evaluation to evaluate the superiority of physiological ventricular pacing (proposed modality) vs. managed ventricular pacing (control) for prevention of persistent AF (PeAF) occurrence in patients with prolonged atrioventricular interval (PR≥180 ms) and indication for pacing: sinus node disease and/or paroxysmal type 1 or 2-second degree AV block.
CONDITIONS
Official Title
Physiological Ventricular Pacing Vs Managed Ventricular Pacing for Persistent AF Prevention in Prolonged AV Interval
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Able to provide informed consent
- Prolonged atrioventricular interval (PR >180 ms)
- Indication for pacemaker implantation due to sinus node disease or paroxysmal type 1 or 2 second-degree AV block
You will not qualify if you...
- Candidates for implantable cardioverter-defibrillator or cardiac resynchronization therapy device
- Severe mitral or aortic valve regurgitation or stenosis
- Prior atrial fibrillation ablation involving left pulmonary veins
- Cardiac surgery within 3 months before pacemaker implantation
- History of long-standing persistent atrial fibrillation
- Permanent third-degree atrioventricular block
- Participation in another clinical trial within the past 3 months
- Pregnancy or intention to become pregnant
- Life expectancy less than 3 years
AI-Screening
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Trial Site Locations
Total: 1 location
1
Elettrofisiologia, Cardiologia, Ospedale di Rovigo
Rovigo, Veneto, Italy, 45100
Actively Recruiting
Research Team
G
Gianni Pastore, MD
CONTACT
F
Franco Noventa, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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