Actively Recruiting

Age: 19Years +
All Genders
NCT06130033

The Physiology of Circulatory Arrest in Humans

Led by University of British Columbia · Updated on 2024-11-13

50

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to better understand what happens in the brain during the dying process. This is a prospective observational study conducted at the end of life in the ICU at VGH. At the time of withdrawal of life sustaining therapies the investigators will monitor brain blood flow and oxygenation. The investigators will also collect blood samples to measure biomarkers of brain dysfunction. This may help us to determine when blood flow to the brain stops and when brain function ceases. This information may provide researchers and the medical community as a whole with important information as to the best timing for organ donation. This study is the first step in commencing a research program related to improving the organ donation process. Our goal is to determine how best to provide high quality organs to those who would otherwise die without an organ transplant.

CONDITIONS

Official Title

The Physiology of Circulatory Arrest in Humans

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age greater than 18 years
  • Anticipated withdrawal of life-sustaining measures within the next 24 hours
Not Eligible

You will not qualify if you...

  • No in-situ arterial line
  • No legally authorized representative
  • Neurological brain death declared

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Vancouver General Hospital

Vancouver, British Columbia, Canada, V5Z1M9

Actively Recruiting

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Research Team

M

Mypinder Sekhon, MD PhD

CONTACT

R

Rebecca Grey, BSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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