Actively Recruiting

Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT04352244

The Physiology of Human Brown Adipose Tissue

Led by Beth Israel Deaconess Medical Center · Updated on 2025-10-31

40

Participants Needed

1

Research Sites

381 weeks

Total Duration

On this page

Sponsors

B

Beth Israel Deaconess Medical Center

Lead Sponsor

J

Joslin Diabetes Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

Brown fat is a type of fat, found in both children and adults, which can produce heat and regulate the body's metabolism and energy use. White fat is the more common type of fat which is used to store extra calories. Understanding more about differences between brown and white fat may allow us to develop new approaches to improve the body's metabolism.

CONDITIONS

Official Title

The Physiology of Human Brown Adipose Tissue

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy adults aged 18 to 75 years undergoing planned clinical procedures at Beth Israel Deaconess Medical Center
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) of 40 kg/m2 or higher
  • History of local or systemic infection with fever or need for antibiotics within 4 weeks
  • Diagnosed diabetes or hemoglobin A1c of 6.5% or higher
  • Use of oral or injectable corticosteroids or other insulin resistance medications within 6 weeks
  • Chronic kidney disease stage 4 or 5, including end-stage renal disease
  • Liver disease with elevated liver enzymes, low albumin, or high bilirubin
  • Active cancer except certain skin cancers
  • Bleeding disorders or low platelet count below 50,000
  • Current addiction to alcohol or substances
  • Mental incapacity, unwillingness, or language barriers preventing understanding or cooperation
  • Use of investigational drugs within 30 days prior to screening
  • Pregnancy, children, prisoners, institutionalized, or other vulnerable populations are not eligible
  • Children are excluded because the study focuses on adult brown adipose tissue

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Beth Israel Deaconess Medical Center

Boston, Massachusetts, United States, 02215

Actively Recruiting

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Research Team

M

Mary Elizabeth Patti, MD

CONTACT

A

Amanda L Sheehan, MSN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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