Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05566483

Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Led by University of Colorado, Denver · Updated on 2025-12-04

30

Participants Needed

1

Research Sites

243 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The primary objectives of this study are to determine whether exercise training is an effective strategy for treatment of Long COVID and characterize the cardiorespiratory and autonomic physiology in these patients to precisely characterize mechanisms contributing to this syndrome.

CONDITIONS

Official Title

Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults 18 years or older with a documented history of COVID-19 infection
  • Symptoms consistent with Long COVID lasting more than 12 weeks after diagnosis
Not Eligible

You will not qualify if you...

  • History of cardiovascular or pulmonary disease before COVID-19 infection
  • Evidence of COVID-related myocardial injury such as myocarditis
  • Deep vein thrombosis or pulmonary embolism following COVID-19 infection
  • Exercise intolerance caused by conditions unrelated to cardiorespiratory or autonomic factors
  • Dependency on supplemental oxygen due to cardiovascular or pulmonary complications from COVID-19

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Hospital

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

W

William K Cornwell, III, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

2

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Physiology of Long COVID-19 and the Impact of Cardiopulmonary Rehabilitation on Quality-of-Life and Functional Capacity | DecenTrialz