Study Comparing Individualized Physiotherapy to Standard Care for People with Amyotrophic Lateral Sclerosis ALS

What this Trial Is About

Researchers are evaluating whether an individualized physiotherapy program tailored to each persons specific motor deficits can better support physical function compared to usual care physiotherapy in people with Amyotrophic Lateral Sclerosis ALS. This study uses diagnostic assessments with a robotic leg press system to identify muscle function strengths and weaknesses. The aim is to develop safer and more patient-centered physiotherapy strategies for ALS patients. Participants are assigned either to an individualized physiotherapy program or to continue with the usual care physiotherapy. About two-thirds of participants receive the tailored program based on their specific functional deficits, while one-third continue standard therapy following typical clinical practice. The study follows participants over a period of 12 months. Throughout the study, participants will engage in physiotherapy sessions approximately three to five times per week, each lasting about 30 minutes. Researchers will assess physical function using tools like the ALS Functional Rating Scale-Revised ALSFRS-R, focusing on activities such as climbing stairs at six months. The study monitors progress and outcomes to understand how different physiotherapy approaches impact ALS motor function and quality of life.

A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)