Actively Recruiting
A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Led by Charlotte Vogt · Updated on 2026-01-15
38
Participants Needed
1
Research Sites
156 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study investigates whether an individualized physiotherapy program, tailored to each patient's specific motor deficits, can better support physical function compared with usual care physiotherapy in people with ALS. The individualized program is guided by diagnostic assessments using a robotic leg press system, which helps identify strengths and weaknesses in muscle function and movement control. Participants will receive either individualized physiotherapy or standard physiotherapy and will be followed for 12 months. The aim of the study is to improve physiotherapy strategies for people with ALS in a safe and patient-centered manner.
CONDITIONS
Official Title
A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of clinically probable, probable laboratory-supported, or definite ALS according to revised El Escorial criteria or upper motor neuron only (OPM classification)
- Age 18 years or older
- Ability to understand study information and provide written informed consent
- Willingness and ability to perform individualized exercise about three to five sessions of 30 minutes per week during the intervention
- Individuals of all sexes and gender identities are eligible
You will not qualify if you...
- Pregnancy
- Having a tracheostomy or continuous assisted ventilation
- Presence of significant non-ALS pulmonary disease
- Having other neurodegenerative or neuromuscular conditions that could affect assessments
- Having a life-threatening disease or impairment that interferes with functional assessment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ALS Clinic
Sankt Gallen, Switzerland, 9007
Actively Recruiting
Research Team
C
Charlotte Vogt
CONTACT
O
Oleksandra Hoptar
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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