Actively Recruiting
A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities
Led by NYU Langone Health · Updated on 2026-03-05
30
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating different remote and in-person aerobic exercise training methods for adults over 45 who are at risk for cardiovascular disease (CVD) but are not meeting recommended physical activity levels. This pilot study aims to compare how acceptable and effective 12 weeks of exercise training delivered via smart-device apps, live virtual classes, self-directed programs, and in-person supervised sessions are for improving physical activity, cardiovascular fitness, and CVD risk factors. Participants will be randomly assigned to one of four exercise approaches: in-person supervised sessions three times per week at a facility with real-time heart rate monitoring; live-streamed virtual classes led by a trainer with real-time feedback; self-directed aerobic exercise with guidance and periodic trainer check-ins using the Map My Fitness app; or training using the Myzone heart rate monitor and app, which provides automated feedback and motivational support three times per week. The exercise intensity and frequency vary slightly depending on the modality. During the study, participants will undergo cardiopulmonary exercise testing before and after the 12-week program to measure fitness changes. Researchers will track weekly moderate to vigorous physical activity minutes, cardiovascular fitness (VO2peak), blood pressure, body mass index, body fat percentage, fasting glucose, and quality of life using the SF-36 survey. Participants will also answer questions about their experience and acceptance of the exercise programs. The study will last up to 13 weeks for each participant.
CONDITIONS
Brief Title
A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 45 years
- At risk for cardiovascular disease with one or more of the following: hypertension, hyperlipidemia, Type 2 Diabetes Mellitus, smoking, obesity, or family history of premature cardiovascular disease
- Not meeting American Heart Association physical activity guidelines for at least 3 months prior to screening
- Hypertension defined as systolic blood pressure 60 140 mm Hg and/or diastolic blood pressure 60 90 mm Hg or use of antihypertensive medication
- Hyperlipidemia defined as LDL cholesterol 60 160 mg/dL or low HDL cholesterol and high triglycerides
- Diabetes mellitus defined by hemoglobin A1c 60 6.5% or fasting glucose 60 126 mg/dL or use of diabetes medication
- Current regular tobacco use
- Obesity with body mass index 60 30 kg/m2
- Family history of early cardiovascular disease in a first-degree relative before age 55 for males or 65 for females
You will not qualify if you...
- Established diagnosis of atherosclerotic cardiovascular disease
- Any serious medical condition preventing safe exercise participation
- Pregnant or planning pregnancy
- Planning to be away for more than 2 weeks during the intervention period
- Any biopsychosocial factors deemed by the investigator to interfere with study participation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 13 weeks
Participants engage in remote or in-person exercise training sessions, including supervised facility-based sessions, live-streamed classes, self-directed aerobic exercise, or using heart rate monitoring devices and apps to guide exercise intensity.
3 to 5 exercise sessions per week depending on the intervention arm
Trial Site Locations
Total: 1 location
1
NYU Langone Health
New York, New York, United States, 10016
Actively Recruiting
Research Team
S
Sean Heffron, MD
R
Ryan Burnett
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
4
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