Actively Recruiting
Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth
Led by McMaster Children's Hospital · Updated on 2025-08-21
20
Participants Needed
2
Research Sites
146 weeks
Total Duration
On this page
Sponsors
M
McMaster Children's Hospital
Lead Sponsor
T
The Hospital for Sick Children
Collaborating Sponsor
AI-Summary
What this Trial Is About
The objective of the study is to assess feasibility, and clinical efficacy of a novel Fecal Microbiota Transplantation protocol for the treatment of pediatric small intestinal bacterial overgrowth (SIBO).
CONDITIONS
Official Title
Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgrowth
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 3-18 years old
- Patients will discontinue antibiotics for at least 1 week prior to FMT
- A diagnosis of SIBO established through lactose breath test (LBT) and showing symptoms of SIBO
You will not qualify if you...
- Participants cannot start new treatments (antibiotics, probiotics, antacids, antimotility) until Week 8 unless clinically needed
- Children under 3 years old are excluded to avoid microbial transmission concerns and ensure ability to perform LBT
- Participants must be referred by their primary or subspecialty physician
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
McMaster Children's Hospital
Hamilton, Ontario, Canada, L8N 3Z5
Actively Recruiting
2
Hospital for Sick Children (SickKids)
Toronto, Ontario, Canada, M5G 1X8
Not Yet Recruiting
Research Team
F
Fariha Chowdhury, BASc, MSc, PhD(c)
CONTACT
N
Nikhil Pai, BSc, MD, CNSC, FRCPC, FAAP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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