Actively Recruiting
Pilot Intervention With Near Infrared Stimulation
Led by University of Florida · Updated on 2025-01-27
24
Participants Needed
2
Research Sites
357 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
M
McKnight Brain Research Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
The current study will test whether age-related cognitive and mood changes in older adults and those will be affected by near infrared (NIR) stimulation. The overall hypothesis, drawn from previous literature, is that exposure to NIR stimulation will have positive effects on brain health and will result in better cognitive and mood performance.
CONDITIONS
Official Title
Pilot Intervention With Near Infrared Stimulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- No evidence of dementia or mild cognitive impairment based on cognitive screening tests within normal limits for age, education, and sex
- Able to provide informed consent and perform cognitive and mood tests on a computer
- At least 8th grade education or ability to read at an 8th grade level
- Willingness to be randomized to receive real or sham intervention
- Able to commit to 12 weeks of intervention plus time for pre- and post-testing
- On stable doses of major medications for at least two months and plan to continue during study participation
- Normal daily functional behavior
You will not qualify if you...
- History of major strokes or significant brain diseases affecting cognition, including brain surgery (except Parkinson's disease subgroup)
- Unstable or uncontrolled medical conditions such as metabolic encephalopathy, HIV, moderate to severe kidney or liver disease
- Current or past major psychiatric disorders including schizophrenia, active psychosis, bipolar disorder, major depressive episode, alcohol or substance abuse within the past six months
- Use of antipsychotics, sedatives, or medications with significant anticholinergic effects
- Use of photosensitive medications like steroids or retin-A within 15 days before intervention
- Diagnosis of active cancer
- Significant motor or visual impairments preventing computer use or color detection
- Participation in cognitive training studies within the last 3 months or current involvement in other cognitive intervention studies
- Inability to undergo brain imaging due to claustrophobia or presence of implants such as pacemakers, heart valves, brain aneurysm clips, orthodontics, non-removable body jewelry, or ferromagnetic shrapnel
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
University of Arizona
Tucson, Arizona, United States, 85721
Actively Recruiting
2
University of Florida
Gainesville, Florida, United States, 32611
Actively Recruiting
Research Team
D
Dawn Bowers, Ph.D.
CONTACT
A
Adam Woods, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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