Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID07243769

A Pilot Randomized Controlled Trial Comparing Core Exercise, Aerobic Exercise, and Combined Exercise in Patients Undergoing Phase II Cardiac Rehabilitation

Led by National Taiwan University Hospital · Updated on 2025-11-24

60

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the impact of adding core muscle endurance training to cardiac rehabilitation (CR) for adults with stable myocardial infarction (MI) or heart failure (HF). This randomized trial aims to clarify the safety and feasibility of core training alongside standard aerobic CR and to compare their effects on fitness, core endurance, balance, symptoms, and quality of life. The study will help guide exercise prescriptions in Phase II CR for this population. Participants are randomly assigned to one of three groups: Pilates-based core endurance training twice weekly, standard aerobic training twice weekly using treadmill or cycle ergometer, or a combined program with one session of each per week. Each session lasts about 60 minutes, supervised with continuous safety monitoring, and the intervention period lasts eight weeks. During the study, participants undergo baseline and post-training assessments including peak oxygen uptake, six-minute walk distance, various core endurance and balance tests, hand grip strength, body composition, and symptom questionnaires. Researchers monitor safety continuously, and participants attend supervised sessions twice per week for eight weeks. The study duration includes initial testing, the training program, and follow-up assessments to evaluate changes in fitness and function.

CONDITIONS

Brief Title

A Pilot Randomized Controlled Trial Comparing Core Exercise, Aerobic Exercise, and Combined Exercise in Patients Undergoing Phase II Cardiac Rehabilitation.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age over 18 years
  • Diagnosed with myocardial infarction or heart failure with stable condition
  • Referred for participation in Phase II cardiac rehabilitation
  • Able to attend training sessions twice a week regularly
Not Eligible

You will not qualify if you...

  • Cardiac surgery within the past three months
  • Presence of pacemaker, defibrillator, or left ventricular assist device
  • Cognitive impairment or dementia preventing understanding or following training
  • Inability to complete cardiopulmonary exercise testing
  • Pregnancy
  • Contraindications to cardiac rehabilitation based on ACSM guidelines, including unstable angina, uncontrolled severe hypertension, orthostatic hypotension, severe aortic stenosis, uncontrolled arrhythmia, decompensated heart failure, third-degree atrioventricular block, acute pericarditis or myocarditis, aortic dissection, acute pulmonary embolism, or other acute medical conditions
  • Refusal to participate in the study

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 8 weeks

Participants undergo an 8-week exercise training program consisting of either core exercise, aerobic exercise, or a combination of both, with sessions twice per week.

Two exercise sessions per week

Trial Site Locations

Total: 1 location

1

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

H

Hung-Jui Chuang, Dr.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

3

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