Actively Recruiting

Phase Not Applicable
Age: 3Years +
All Genders
NCT06735625

Pilot Study "AHSP as a Biomarker of Sickle Cell Disease in a Population of Adults and Children"

Led by Centre Hospitalier de Saint-Denis · Updated on 2025-04-02

100

Participants Needed

1

Research Sites

97 weeks

Total Duration

On this page

Sponsors

C

Centre Hospitalier de Saint-Denis

Lead Sponsor

I

Inserm U955

Collaborating Sponsor

AI-Summary

What this Trial Is About

Evaluation of AHSP concentration in total blood as a biomarker in adult and pediatric sickle cell patients

CONDITIONS

Official Title

Pilot Study "AHSP as a Biomarker of Sickle Cell Disease in a Population of Adults and Children"

Who Can Participate

Age: 3Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults older than 15 years and 6 months
  • Children aged 3 years to 15 years and 6 months
  • Known SS or Sb20 sickle cell phenotypes
  • Control adults older than 15 years and 6 months without hemoglobinopathy
  • Control children aged 3 to 15 years and 6 months without hemoglobinopathy
  • Control adults followed for hematological disease, prolonged fever, inflammatory syndrome, auto-inflammatory or systemic disease, or general health deterioration
  • Control children followed for suspected precocious puberty, growth delay, or neurodevelopmental disorder
  • Blood sample planned as part of medical care
Not Eligible

You will not qualify if you...

  • Hemoglobin disorders other than sickle cell disease (for sickle cell patients)
  • Hemoglobinopathies other than sickle cell disease (for control patients)
  • Blood transfusion within the last 3 months
  • Chronic active viral diseases such as hepatitis B, C, or HIV
  • Current infections or known inflammatory diseases
  • Known hyperthyroidism or hypothyroidism or treatment with levothyroxine
  • Active tumor disease or remission under 5 years
  • Current oral corticosteroid therapy
  • Participation in interventional biomedical research
  • Opposition to participation by the patient or parents
  • Not affiliated to a social security system

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Hospitalier de Saint-Denis

Saint-Denis, France, 93200

Actively Recruiting

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Research Team

S

Stéphanie NGO, Coordinating Investigator

CONTACT

S

Stéhanie COSSEC, Project Coordinator

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

4

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