Actively Recruiting

Phase Not Applicable
Age: 18Years - 70Years
All Genders
NCT05853107

Pilot Study of AuTNA I

Led by Eye & ENT Hospital of Fudan University · Updated on 2025-09-19

7

Participants Needed

1

Research Sites

146 weeks

Total Duration

On this page

Sponsors

E

Eye & ENT Hospital of Fudan University

Lead Sponsor

F

Fudan University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of the study is to evaluate: 1. Safety of AuTNA I for subretinal implantation in patients with retinitis pigmentosa; 2. Efficacy of AuTNA I for subretinal implantation in patients with retinitis pigmentosa.

CONDITIONS

Official Title

Pilot Study of AuTNA I

Who Can Participate

Age: 18Years - 70Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 70 years
  • Clinically diagnosed with retinitis pigmentosa based on specific retinal changes
  • No or suspicious light perception in the eye selected for AuTNA I implantation
  • Intact inner retinal structure on OCT with no macular retinal or choroidal neovascularization
  • Willing to participate and able to sign informed consent
Not Eligible

You will not qualify if you...

  • Conditions interfering with AuTNA I function such as ocular trauma, retinal detachment, glaucoma, or severe uveitis
  • Uncontrolled systemic diseases including hypertension and diabetes
  • Allergic constitution
  • Conditions preventing fundus observation like corneal opacity
  • Ocular diseases unsuitable for implantation surgery such as corneal ulcers
  • Habit of rubbing the eyes
  • Compromised liver, kidney, or coagulation functions
  • Pregnancy, lactation, or planning pregnancy within 6 months
  • History of epilepsy or serious psychiatric illness
  • Other diseases affecting vision
  • Participation in other clinical trials within 1 month
  • Any other conditions deemed inappropriate by the researcher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chunhui Jiang

Shanghai, Shanghai Municipality, China, 200030

Actively Recruiting

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Research Team

C

Chunhui Jiang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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