Actively Recruiting

Phase Not Applicable
Age: 12Years +
All Genders
NCT07321366

Pilot Study on the Efficacy and Tolerability of Cryoneurolysis Treatment in Disabling and/or Painful Hypertonia of the Shoulder and Elbow in Patients With Cerebral Palsy

Led by Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française · Updated on 2026-01-08

40

Participants Needed

1

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main objective of this study is to evaluate the achievement of personalised short- and medium-term objectives of this selective treatment of hypertonia by ultrasound-guided perineural percutaneous cryoneurolysis at the shoulder and elbow, in a population of patients with cerebral palsy with spastic, dyskinetic or dyskinetic, or mixed disorders.

CONDITIONS

Official Title

Pilot Study on the Efficacy and Tolerability of Cryoneurolysis Treatment in Disabling and/or Painful Hypertonia of the Shoulder and Elbow in Patients With Cerebral Palsy

Who Can Participate

Age: 12Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with cerebral palsy treated at CMCR des Massues, regardless of gross motor or manual ability levels
  • Disabling and/or painful muscle hyperactivity in shoulder and/or elbow
  • Age over 12 years
  • At a therapeutic impasse: contraindicated or refusing surgery, ineffective or contraindicated oral treatments, or short duration of toxin injection efficacy (<3 months)
  • Informed consent signed by patient or legal representative
  • Affiliated with a social security scheme
Not Eligible

You will not qualify if you...

  • Botulinum toxin injection within 3 months prior to inclusion
  • Change in analgesic or antispastic treatment within 5 weeks prior to inclusion
  • Refusal to allow use of medical data for research
  • Contraindication to peripheral motor block or cryoneurolysis (e.g., haemostasis disorder, skin infection, Raynaud's syndrome, cryoglobulinaemia, cold urticaria)
  • Pregnant or breastfeeding patients
  • Cognitive or behavioral disorders preventing study participation or consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CMCR des Massues

Lyon, Rhône, France, 69003

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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