Pilot Study Testing a Nurse-Led Education Program to Increase Genetic Testing in Adults With Solid Tumors Starting or Changing Systemic Therapy

What this Trial Is About

Genetic factors play a key role in the risk of developing various cancers, with important implications for patients and their families. This research investigates a nurse-led approach to increase genetic counseling and testing GCT among adults with solid tumors. Despite guidelines recommending GCT, many patients do not receive it, partly due to barriers in referral by oncologists. The study focuses on improving GCT uptake through enhanced education by oncology nurses in community cancer centers. Participants are randomized into two groups one receiving an enhanced education session led by trained oncology nurses, and the other receiving usual care education. The enhanced education includes detailed information on GCT, eligibility assessment, referral ordering if agreed upon, and follow-up reminders to ensure referrals are processed. Usual care provides standard treatment education without targeted genetic testing information. This pilot study aims to evaluate the effectiveness, acceptability, and feasibility of this nurse-led intervention. During the study, researchers track the percentage of patients who proceed to GCT consultation and referral, as well as timing from referral to consultation and testing completion. The study lasts about nine months, with ongoing monitoring of these outcomes. Patients will receive education sessions, and nurses will facilitate referrals and follow-up communications to support genetic testing uptake. The study is conducted by the University of California, Davis, and focuses on adult cancer patients starting or switching systemic therapy.

A Pilot Study of Genetic Testing Uptake Through Enhanced Oncology Nurse-Led Intervention