Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT05217160

Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers

Led by The Metis Foundation · Updated on 2022-02-01

24

Participants Needed

1

Research Sites

55 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is intended to provide information from subjects who currently have painful, chronically open wounds and assess the pain reduction capacity of KeraStat® Gel with Morphine. In gathering data from subjects who have baseline pain from their chronically open wounds, the investigators can then evaluate the capacity of KeraStat® Gel plus Morphine in reducing the subjects daily pain levels, pain associated with dressing changes, and pain medication consumption.

CONDITIONS

Official Title

Pilot Study: KeraStat® Gel for Topical Delivery of Morphine for Management of Non-Healing, Painful Open Wounds and Ulcers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Subjects aged 18 years or older able to provide informed consent
  • Ulcer size between 1 and 300 cm2
  • Undermining or tunneling less than 3 cm from wound margin
  • Wound grossly free of necrotic and/or infected tissue
  • Baseline pain score of at least 2 on the Visual Analog Scale (VAS)
Not Eligible

You will not qualify if you...

  • Known allergy to standard care, KeraStat4 Gel ingredients, or Morphine
  • Wounds with heavy or high-volume exudate or necrotic tissue
  • Clinical signs of infection or wound contamination
  • Unable to complete VAS pain score or pain journal
  • Pregnant or nursing
  • Prisoners
  • Any condition that investigator determines compromises safety or study completion

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

South Texas Aesthetic and Reconstructive Surgery

San Antonio, Texas, United States, 78229

Actively Recruiting

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Research Team

V

Victoria Diaz, RN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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