Actively Recruiting
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Led by Ohio State University Comprehensive Cancer Center · Updated on 2025-10-03
43
Participants Needed
1
Research Sites
213 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Breast cancer (BC) is the most frequently diagnosed cancer in women. Systemic cancer treatments are an important contributor to dramatic improvements in the long-term survival of women with BC. However, cancer treatment can lead to cognitive impairment and declines in quality of life in women with BC. Many cancer survivors experience memory and brain function decline following chemotherapy which can last for years. A newer diet pattern, Mediterranean-DASH \[Dietary Approaches to Stop Hypertension\] Intervention for Neurodegenerative Delay (MIND), was shown to help with protecting brain functions. The MIND diet is high in anti-inflammatory nutrients (e.g., omega-3 polyunsaturated fatty acids (PUFAs), carotenoids, B-vitamins, and polyphenols) and limits the intake of brain-unhealthy foods (i.e., butter/margarine, cheese, red meat, fried foods, pastries, and sweets), which may help alleviate negative cognitive outcomes from cancer treatments. This randomized controlled trial aims to investigate the effect of the MIND diet on cognitive functions in women with invasive BC starting systemic therapies.
CONDITIONS
Official Title
Pilot Study of a MIND Diet Intervention in Women Undergoing Active Treatment for Breast Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with stage II-IV hormone receptor-positive breast cancer
- Post-menopausal (at least 1 year since last period, on ovarian suppression medication, or had ovaries removed)
- Within 4 weeks before or 12 weeks after starting initial systemic therapies like chemotherapy or targeted therapies
- Able to access and use internet resources including video calls using Zoom
- English speaking
You will not qualify if you...
- History of dementia, stroke, traumatic brain injury, brain metastasis, or other cognitive impairment conditions
- MIND diet score greater than 8
- Unwilling or unable to eat more than 2 types of MIND diet foods
- Currently receiving insulin therapy for diabetes
- Diagnosed with triple negative breast cancer
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
T
The Ohio State University Comprehensive Cancer Center
CONTACT
K
Kellie R Weinhold, MS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here