Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06109909

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

Led by VA Office of Research and Development · Updated on 2025-12-16

36

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing photosensitivity symptoms in Veterans with a history of mild traumatic brain injury (mTBI). The study will also complete resting-state MRI scans to assess neurophysiological markers of photosensitivity and changes associated with LIP-tES intervention.

CONDITIONS

Official Title

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 18 to 65 years
  • Documented history of mild traumatic brain injury at least 6 months before the first study visit
  • Documented symptoms of photosensitivity
  • Eye exam within the past 12 months showing best-corrected visual acuity of 20/20 or better, normal pupil function, normal color vision, no abnormalities on OCT scan, and normal Humphrey Visual Field test
Not Eligible

You will not qualify if you...

  • History of strabismus or amblyopia
  • Significant clouding of the eye media that reduces light entering one or both eyes
  • Past or current retinal or optic nerve disease in one or both eyes
  • History of stroke or visual neglect
  • History of neurodegenerative diseases such as Parkinson's or multiple sclerosis
  • History of epilepsy or seizures
  • History of motor tics
  • Current use of medications or substances that severely affect pupil response or increase photosensitivity
  • Impaired decision-making ability
  • Illiteracy or inability to understand English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

Boston, Massachusetts, United States, 02130-4817

Actively Recruiting

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Research Team

F

Francesca C Fortenbaugh, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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