Actively Recruiting
Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease
Led by Oregon Health and Science University · Updated on 2025-01-13
150
Participants Needed
1
Research Sites
95 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a research study investigating elevated homocysteine in the blood of patients with Parkinson's disease who are currently receiving treatment with levodopa. We are evaluating if elevated homocysteine can be corrected using open label B vitamin therapy, as well as the impact of homocysteine levels on cognitive function.
CONDITIONS
Official Title
Pilot Study of Open Label Homocysteine Management Therapy in Levodopa-treated Parkinson's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of probable Parkinson's Disease according to Movement Disorders Society criteria
- Currently treated with levodopa at a minimum dose of 300 mg/day
- Montreal Cognitive Assessment (MOCA) score of 15 or higher
- Ability to provide informed consent
- Age between 40 and 90 years
- Estimated glomerular filtration rate of 60 or higher
- No history of uncontrolled hypertension
- Not using insulin
You will not qualify if you...
AI-Screening
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Trial Site Locations
Total: 1 location
1
Oregon Health & Science University (OHSU)
Portland, Oregon, United States, 97239
Actively Recruiting
Research Team
M
Madeline Armendariz Sullivan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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