Actively Recruiting
A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity
Led by M.D. Anderson Cancer Center · Updated on 2026-04-16
100
Participants Needed
1
Research Sites
164 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn about the relationship between changes in pupil size and reactivity and the start of neurological side effects in patients after receiving CAR-T cell therapy.
CONDITIONS
Official Title
A Pilot Study for Pupillary Assessment to Predict CAR-T Related Neurotoxicity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- All genders eligible
- Diagnosed with DLBCL, PMBCL, tFL, or follicular lymphoma and receiving Axi-cel CAR-T therapy inpatient at MD Anderson Cancer Center
- Able to understand and willing to sign informed consent
You will not qualify if you...
- Already received CAR-T cell therapy
- Unwilling or unable to comply with study requirements including pupillometer assessment
- Has a condition that poses unacceptable risk as judged by the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
R
Ranjit Nair, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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