Pilot Study to Evaluate a New Commercial Toothpaste for Periodontitis Supportive Care Using Twice Daily Brushing Over 3 Months

What this Trial Is About

Researchers are evaluating the effectiveness of a commercial toothpaste containing a novel compound aimed at supporting a healthy oral microbiome in people with periodontitis. This multi-center controlled clinical study focuses on volunteers who receive professional tooth cleaning every 3 to 6 months during a non-treatment period between supportive periodontitis therapy sessions. The study aims to determine how well this toothpaste works when used at home. Participants will brush their teeth twice daily with the allocated toothpaste for three months. The toothpaste includes common ingredients like sodium fluoride and cleaning agents, plus a new compound designed to benefit the oral microbiome. The study involves monitoring the participants during this 3-month period while they maintain their usual professional tooth cleaning routine. During the study, participants will be assessed before and after the 3 months of toothpaste use to evaluate its efficacy. Researchers will collect data on oral health, including the presence of specific bacteria and plaque control. Participants will be monitored for safety and adherence, and the main outcome is the toothpastes effect on the oral microbiome after 12 weeks of use.

A Pilot Study to Test the Efficacy of a Commercial Toothpaste (Cosmetic Product)