Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06712446

A Pilot Study of Transcranial Magnetic Stimulation Plus Episodic Future Thinking for Methamphetamine Use Disorder

Led by The University of Texas Health Science Center, Houston · Updated on 2026-03-05

20

Participants Needed

1

Research Sites

92 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to assess impact of repetitive transcranial magnetic stimulation (rTMS)+Episodic Future Thinking (EFT) vs. sham rTMS+EFT on delay discounting and methamphetamine (MA) demand, on vividness of future positive events during EFT training and on frequency of episodic thinking during the week following EFT training

CONDITIONS

Official Title

A Pilot Study of Transcranial Magnetic Stimulation Plus Episodic Future Thinking for Methamphetamine Use Disorder

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Meet DSM-5 criteria for primary methamphetamine use disorder
  • Be fluent in English and able to understand the consent form
Not Eligible

You will not qualify if you...

  • Current DSM-5 diagnosis for any illicit substance use disorder other than methamphetamine and marijuana
  • Current DSM-5 diagnosis of moderate or greater severity for alcohol and marijuana use disorder
  • Any medical, neurological, psychiatric, or physical condition that may interfere with study completion or safety
  • Current or recent suicidal or homicidal ideation or behavior based on specific assessments
  • Medical implants contraindicating TMS within 30 cm of the coil
  • History of brain surgery
  • History of intracranial lesion or conditions causing increased intracranial pressure, or recent severe headaches or vision loss
  • Moderate-to-severe heart disease
  • History of stroke
  • Use of certain medications increasing seizure risk or unsafe doses of antidepressants/antipsychotics
  • Personal or family history of epilepsy or seizures
  • Serious head injury with loss of consciousness
  • Impending incarceration
  • Pregnant or nursing females
  • Inability to read, write, or speak English
  • For ages 18-21: any risk factor for neurocardiogenic syncope

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

H

Heather Webber, PhD

CONTACT

J

Jessica Vincent

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

QUADRUPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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