Actively Recruiting

Phase Not Applicable
Age: 9Years +
All Genders
Healthy Volunteers
NCT07009509

Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

Led by University of Colorado, Denver · Updated on 2025-07-15

1166

Participants Needed

1

Research Sites

115 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this pilot study is to determine the feasibility of a randomized trial of the YES-CAN! (Youth Engaged Strategies to Change Adolescent Norms) program to prevent nicotine vaping among adolescents. The program integrates the following evidence-based strategies: youth-adult collaboration; youth-developed narrative videos to convey health messages; peer leaders as change agents; and sustained implementation to change the normative environment. Two middle/high school communities will receive the YES-CAN! intervention. In each school community, a trained teacher will deliver a credit-earning middle or high school class to 25-30 middle or high school students, who will produce 6-8 short videos intended to increase refusal skills; promote stress management and positive coping; change social norms; prevent vaping initiation; and promote vaping cessation among current users. Videos will use a narrative approach and integrate known determinants of vaping. Middle or high school students will collaborate with the teacher and researchers to develop discussion guides and skills-building activities based on best practices for substance use prevention. In 6-8 sessions, middle or high school students will deliver their videos to all students in the associated middle school. A text messaging or other media component will reinforce and boost the effectiveness of the classroom sessions. Aims for this pilot/feasibility study are: 1. To determine the feasibility and acceptability of implementing the YES-CAN! program 2. To determine the feasibility and acceptability of the research protocols that will be used in a future efficacy trial

CONDITIONS

Official Title

Pilot Study of the YES-CAN! Program to Prevent Youth Nicotine Vaping

Who Can Participate

Age: 9Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children enrolled in middle school grades 6-8 and high school grades 9-12 (age approximately 10-13 and 14-17)
  • Adults over age 18 involved in the educational system
Not Eligible

You will not qualify if you...

  • Not able to read and write in English or Spanish

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

L

Lori A Crane, PhD, MPH

CONTACT

N

Nancy L Asdigian, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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