Actively Recruiting
A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes
Led by University of Manitoba · Updated on 2026-05-14
30
Participants Needed
1
Research Sites
530 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Improvements in burn care have resulted in increased survival. Despite these improved outcomes one of the leading challenges of burn care remains providing adequate analgesia during routine wound care and dressing changes. The traditional use of narcotics is challenging as the therapeutic window between analgesia and suppression of breathing becomes narrow with the intense pain and high doses of narcotics needed for dressing changes.
CONDITIONS
Official Title
A Pilot Trial of Disposable Nitrous Oxide Canisters in Providing Pain Control During Burn Dressing Changes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult burn patients admitted to the Health Sciences Centre
- Total body surface area burned of 5-20%
You will not qualify if you...
- Admitted to intensive care unit
- Unable to participate in the measurement outcomes (sedated, cognitively impaired, unable to understand English or visually impaired)
- Medical condition that precludes using nitrous oxide (respiratory disease and significant cardiovascular disease)
- Pregnant
- Physically unable to hold the canister
- Oxygen saturation below 90% on room air
- Face burn
- Pre-injury narcotics use (relative exclusion)
- Use of IV ketamine
- Pre-existing lung injury
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Manitoba
Winnipeg, Manitoba, Canada, R3A 1R9
Actively Recruiting
Research Team
S
Sarvesh Logsetty, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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