Actively Recruiting
Pilot Study of Vitamin A and Nicotinamide Supplements for Kidney Transplant Patients with Skin Cancer History
Led by Rhode Island Hospital · Updated on 2026-03-20
30
Participants Needed
1
Research Sites
8 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the safety and feasibility of taking oral nicotinamide, a form of vitamin B3, together with vitamin A in people who have received a kidney transplant and have a history of skin cancer. This early-phase clinical trial aims to gather preliminary data that may support future studies focused on preventing cancer in this high-risk group. Participants will be randomly assigned to one of two groups one group will receive vitamin A 1,000 micrograms retinyl palmitate and nicotinamide 500 mg twice daily, while the other group will take identical placebo pills twice daily. The treatment period lasts for six months, during which participants will take the assigned pills regularly. Throughout the study, researchers will monitor changes in blood levels of vitamin A and nicotinamide at six months. Participants will be assessed for safety and treatment adherence. This trial includes follow-up visits and evaluations to track these changes and ensure participant safety over the course of the study.
CONDITIONS
Brief Title
Pilot Trial of Supplemental Vitamin A and Nicotinamide
Research Team
E
Eunyoung Cho, ScD
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