Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06287866

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

Led by University of California, Davis · Updated on 2025-09-18

50

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to compare two methods for healing wounds on the scalp after Mohs micrographic surgery, a procedure to remove skin cancer. The study focuses on how quickly wounds heal when left to close naturally (second intention) versus when treated with a pinch graft, where a thin piece of skin is taken from another area and placed on the wound. Researchers want to understand which method helps wounds heal faster and with fewer complications. Participants will be randomly assigned to one of two groups: one will receive second intention wound healing where the wound is left open to heal on its own, and the other will receive pinch graft treatment involving numbing the area, shaving thin skin from a donor site, and placing it onto the wound. The study will monitor healing progress over 1 to 8 weeks and follow up at 3 months to assess scar appearance. During the study, participants will be asked to return for follow-up visits and send weekly messages until their wound is healed using a digital health platform called MyChart. Researchers will measure the time it takes for the wound to re-epithelialize (heal) and evaluate scar quality using the Patient Observer Scar Assessment Score at 3 months. The study monitors healing speed and scar outcomes while ensuring patient communication and adherence throughout the process.

CONDITIONS

Brief Title

Pinch Grafting Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects on the Scalp

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age or older
  • Able to give informed consent themselves
  • Patient scheduled for cutaneous surgical procedure on the scalp with predicted second intention closure
  • Willing to return for follow up visit
  • Active user of MyChart
  • Willing to send weekly messages until wound is healed
Not Eligible

You will not qualify if you...

  • Incarceration
  • Under 18 years of age
  • Pregnant women
  • Unable to understand written and oral English
  • Scalp wounds with planned primary repair reconstruction
  • Surgical defects with bone exposure
  • No MyChart access or use

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 1 to 8 weeks

Participants receive either pinch graft reconstruction or second intention wound healing for Mohs surgical defects on the scalp to compare healing times and complication rates.

Weekly visits until wound is healed

Follow-up

Duration - Up to 3 months

Participants undergo scar assessments to evaluate healing outcomes after treatment.

1 visit at 3 months post-treatment

Trial Site Locations

Total: 1 location

1

University of California, Davis - Dermatology Department

Sacramento, California, United States, 95816

Actively Recruiting

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Research Team

J

John Robb, BS, BA

K

Keemberly Kim, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

Frequently Asked Questions

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Published Research Related To This Trial

[Role of cutaneous pinch grafts in the healing of patients with dystrophic epidermolysis bullosa wounds: report of four cases].

O Claude, J P Binder, K Bustamante...

https://pubmed.ncbi.nlm.nih.gov/15963838

Pinch Grafts Versus Second Intention Wound Healing for Mohs Micrographic Surgery Defects Below the Knee: A Prospective Randomized Trial.

Tyler J Willenbrink, David G Brodland

https://pubmed.ncbi.nlm.nih.gov/39088685