Study of Pipeline Embolization Device for Treating Intracranial Aneurysms Observing Safety, Effectiveness, and Blood Flow Changes In Adults Aged 22 to 75 Years

What this Trial Is About

Researchers are collecting clinical, laboratory, and imaging data from adults aged 22 to 75 years with intracranial aneurysms who undergo Pipeline embolization device implantation. This observational study aims to observe the safety, effectiveness, and blood flow changes after treatment with the Pipeline embolization device, focusing on both saccular and non-saccular aneurysms. The study is sponsored by Zhujiang Hospital and seeks to advance understanding of this treatments impact over time. Participants receive the Pipeline embolization device implantation with or without the shield technique based on availability and surgeon preference. The study includes patients with aneurysms sized between 3 to 25 mm, with follow-up scheduled to monitor outcomes. Two main groups include those with saccular aneurysms and those with non-saccular aneurysms such as fusiform or dissecting types. During the study, researchers will assess aneurysm occlusion rates at one year, incidence of in-stent stenosis, and perioperative complications within one month. Participants will be monitored through clinical evaluations, imaging scans, and laboratory tests to evaluate the treatments effect on blood flow and vessel condition. Follow-up visits are required to ensure adherence and assess functional prognosis, with ongoing observation until the studys completion in 2030.

Pipeline Embolization for Intracranial Aneurysms