Actively Recruiting
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients
Led by University of Rochester · Updated on 2026-03-23
100
Participants Needed
19
Research Sites
265 weeks
Total Duration
On this page
Sponsors
U
University of Rochester
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
To investigate the effect of VTA ablation at the time of LVAD implant to see if it can reduce the incidence of VTA after surgery
CONDITIONS
Official Title
The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age > 18 years
- Presence of advanced cardiomyopathy (all INTERMACS classifications) and eligibility for LVAD implant as decided by the Heart Failure clinical team
- Implanted cardioverter defibrillator (ICD) at any time in the past with remote monitoring or planned ICD (or implantable cardiac monitor if ICD cannot be implanted) during the LVAD implant hospitalization
- History of treated or monitored sustained ventricular tachycardia (VT) or ventricular fibrillation (VF) lasting more than 30 seconds within the past 5 years
You will not qualify if you...
- Past successful ventricular tachyarrhythmia ablation without recurrent VTA before LVAD implant (patients with recurrent VTA after ablation and before LVAD implant are eligible)
- Participation in other clinical trials (observational registries allowed with approval)
- Unable or unwilling to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 19 locations
1
Banner University Medical Center
Phoenix, Arizona, United States, 85006
Actively Recruiting
2
UCLA Cardiac Arrthmia Center
Los Angeles, California, United States, 90095
Actively Recruiting
3
University of California San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
4
Medstar Washington Hospital Center
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
5
Piedmont Heart Institute
Atlanta, Georgia, United States, 30309
Actively Recruiting
6
Emory University
Atlanta, Georgia, United States, 30322
Actively Recruiting
7
Ascension St. Vincent Indianapolis
Indianapolis, Indiana, United States, 46260
Actively Recruiting
8
Univedrsity of Louisville
Louisville, Kentucky, United States, 40202
Actively Recruiting
9
Johns Hopkins University
Baltimore, Maryland, United States, 21287
Actively Recruiting
10
Tufts Medical Center
Boston, Massachusetts, United States, 02111
Actively Recruiting
11
Henry Ford Health
Detroit, Michigan, United States, 48202
Actively Recruiting
12
Columbia University Medical Center
New York, New York, United States, 10026
Actively Recruiting
13
University of Rochester
Rochester, New York, United States, 14642
Actively Recruiting
14
Cleveland Clinic
Cleveland, Ohio, United States, 44195
Actively Recruiting
15
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
16
UPMC
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
17
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
18
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232
Actively Recruiting
19
Houston Methodist Hospital
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
A
Ann Colasurdo
CONTACT
K
Kathy Honsinger
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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