Actively Recruiting
A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Catheter in Patients With Acute Ischemic Stroke
Led by Neuravi Limited · Updated on 2026-05-08
74
Participants Needed
15
Research Sites
77 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to assess the safety and the effectiveness of the Adaptive Tip Catheter (ATC) used as a first line direct aspiration thrombectomy technique for patients suffering of an acute ischemic stroke.
CONDITIONS
Official Title
A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Catheter in Patients With Acute Ischemic Stroke
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 90 years at the time of consent
- Signs and symptoms of acute ischemic stroke in the anterior circulation treatable by endovascular thrombectomy
- Endovascular treatment can begin within 24 hours from last known well time
- Baseline National Institutes of Health Stroke Scale (NIHSS) score of 6 or higher
- Baseline Alberta Stroke Program Early CT Score (ASPECTS) of 3 or higher
- Signed and dated informed consent form or approved emergency procedure consent obtained
You will not qualify if you...
- Known pregnancy or breastfeeding
- Life expectancy less than 90 days before stroke onset
- Known bleeding disorders, coagulation factor deficiency, or oral anticoagulant therapy with INR greater than 3.0
- Symptoms or imaging showing stroke in multiple vascular territories or bilateral stroke
- Intracranial occlusion considered chronic by history or imaging
- Recent or fresh hemorrhage seen on CT or MRI
- CT or MRI showing brain swelling (mass effect)
- Currently in another interventional clinical trial that may affect study results
- Cerebral arterial disease affecting treatment or outcome (e.g., vasculitis)
- Blood vessel blockages or narrowing preventing device access or requiring acute stenting
- Excessive blood vessel twisting preventing catheter access
- Baseline expanded thrombolysis in cerebral infarction (eTICI) score greater than 1
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 15 locations
1
UZ Antwerpen
Edegem, Belgium, 2650
Actively Recruiting
2
Ghent University Hospital
Ghent, Belgium, 9000
Actively Recruiting
3
Universitair Ziekenhuis Leuven
Leuven, Belgium, 3000
Actively Recruiting
4
CHU Bordeaux
Bordeaux, France, 33076
Not Yet Recruiting
5
CHU Nantes
Nantes, France, 44093
Not Yet Recruiting
6
CHU Pitie Salpetriere
Paris, France, 75013
Not Yet Recruiting
7
Centre Hospitalier Universitaire de Toulouse - Hopital Purpan
Toulouse, France, 31059
Not Yet Recruiting
8
CHRU de Tours
Tours, France, 37000
Not Yet Recruiting
9
Universitaetsklinikum Heidelberg
Heidelberg, Germany, 69120
Not Yet Recruiting
10
Universitatsklinikum Schleswig Holstein Kiel
Kiel, Germany, 24105
Not Yet Recruiting
11
Universitaetsmedizin Mainz
Mainz, Germany, 55101
Not Yet Recruiting
12
Stadtisches Klinikum Solingen gemeinnutzige GmbH
Solingen, Germany, 42653
Not Yet Recruiting
13
Beaumont Hospital
Dublin, Ireland, 00000
Not Yet Recruiting
14
VUMC Amsterdam
Amsterdam, Netherlands, 1105 AZ
Withdrawn
15
Maastricht University Medical Centre
Maastricht, Netherlands, 6229 HX
Not Yet Recruiting
Research Team
A
Adriana Popovici
CONTACT
A
Arnaud Nicolas, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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