Actively Recruiting
PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-11-28
60
Participants Needed
2
Research Sites
125 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A multicenter international prospective observational pharmacological study in adult patients (≥18 years) treated with ceftazidime/avibactam (CAZ/AVI) alone or with CAZ/AVI plus fosfomycin (FOS) for infection due to carbapenem-resistant Enterobacterales (CRE) (KPC and/or OXA-48).
CONDITIONS
Official Title
PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed informed consent
- Age 18 years or older
- Adult patients treated for at least 48 hours with ceftazidime/avibactam or ceftazidime/avibactam plus fosfomycin for a microbiologically confirmed CRE infection
You will not qualify if you...
- Polymicrobial or mixed infections except for cases with multiple Enterobacterales susceptible to study drugs
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Bologna, Italy, 40138
Actively Recruiting
2
Instituto de Biomedicina de Sevilla (IBiS), Hospital Virgen Macarena/CSIC/Universidad de Sevilla
Seville, Seville, Spain, 41013
Actively Recruiting
Research Team
M
Maddalena Giannella, MD PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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