Plant-dominant low-protein diet versus standard care in adults with chronic kidney disease stages 3-5: A randomized controlled trial protocol.
Joelle Abi Kharma, Rana Sultan, Rana Rizk...
https://pubmed.ncbi.nlm.nih.gov/42155424/Actively Recruiting
Led by Lebanese American University · Updated on 2025-04-17
48
Participants Needed
1
Research Sites
N/A
Total Duration
This clinical trial is focused on adults with chronic kidney disease CKD to evaluate if a plant-dominant low protein diet PLADO can reduce metabolic acidosis, a key factor in CKD progression. Researchers aim to determine whether the PLADO diet is more effective than the standard-of-care CKD diet and to assess its safety, practicality, and cost-effectiveness. The trial is a randomized controlled study led by Lebanese American University.
CONDITIONS
PLADO for Conservative Management of CKD
R
Rana Rizk, PhD, MS, MPH, LD
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Lebanese American University
Lead Sponsor
Zayed University
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months with an additional 3 months follow-up
Participants receive either a low protein plant-dominant diet (PLADO) or the standard-of-care diet. The nutrition education intervention includes a primary face-to-face education/counseling session followed by monthly face-to-face follow-up sessions for 6 months, and an additional follow-up session after 3 months. At each visit, participants are assessed and receive stage-based education and counseling to support adherence.
1 baseline visit and monthly visits for 6 months, plus 1 visit after 3 months
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Joelle Abi Kharma, Rana Sultan, Rana Rizk...
https://pubmed.ncbi.nlm.nih.gov/42155424/Lebanese American University
Lead Sponsor
Zayed University
Collaborating Sponsor