Actively Recruiting

Phase 2
Age: 25Years - 65Years
MALE
Healthy Volunteers
NCT07361120

Plan A Occlusion and Reversal System Feasibility Study

Led by Next Life Sciences · Updated on 2026-01-22

40

Participants Needed

1

Research Sites

34 weeks

Total Duration

On this page

Sponsors

N

Next Life Sciences

Lead Sponsor

C

Clinico Pty Ltd

Collaborating Sponsor

AI-Summary

What this Trial Is About

Prospective, multicenter, single-arm, open label, interventional clinical trial investigating the safety and effectiveness of the Plan A Male Contraceptive System to occlude the vas deferens to block the passage of sperm and then be reversed to subsequently allow the passage of sperm through the vas deferens.

CONDITIONS

Official Title

Plan A Occlusion and Reversal System Feasibility Study

Who Can Participate

Age: 25Years - 65Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Male seeking and suitable for vasectomy as long-term contraception
  • Signed informed consent form before any study procedures
  • Aged 25 to 65 years
  • Body Mass Index (BMI) less than 31 kg/m2
  • Good health confirmed by medical history, physical exam, and lab tests
  • Normal semen analysis based on two samples
  • Investigator deems subject suitable for vasectomy
  • Agreement to use effective contraception until vasectomy
  • Lives near trial site or agrees to provide semen samples at site or lab
Not Eligible

You will not qualify if you...

  • Absence of one or both vasa or abnormal scrotal conditions making subject unsuitable
  • Prior testicular surgery, injury, or vasectomy reversal
  • Recurrent pain during ejaculation
  • Known allergy to sulfur-containing products or severe reaction to implantable devices
  • Current local genital infections unless resolved
  • History of prostatitis or benign prostatic hypertrophy needing treatment
  • Prior chemotherapy
  • Known bleeding disorders
  • Taking medications affecting sperm count or ejaculation
  • Cystic fibrosis
  • History of inguinal hernia repair
  • Vulnerable subjects (e.g., cognitive challenges, incarcerated)
  • Participation in other investigational studies within 30 days
  • Site staff or family of site staff involved in study
  • Investigator concerns about safety or compliance
  • Any condition interfering with evaluation or safety interpretation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Western Urology

Maribyrnong, Victoria, Australia, 3032

Actively Recruiting

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Research Team

D

Darlene Walley R Chief Executive Officer, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

TREATMENT

Number of Arms

2

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