Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07268326

Plant-Based Diet for Patients With Rheumatoid Arthritis

Led by Center for Clinical Research and Prevention · Updated on 2026-03-18

180

Participants Needed

2

Research Sites

154 weeks

Total Duration

On this page

Sponsors

C

Center for Clinical Research and Prevention

Lead Sponsor

G

Glostrup University Hospital, Copenhagen

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to evaluate the effect of a plant-based diet (PBD) intervention in adults with Rheumatoid Arthritis (RA) on disease activity. The investigators hypothesize that if patients with RA follow a 100% PBD over a 16-week period it will lead to improvements in: \- Disease activity (measured by DAS28), including reduction in symptoms and overall improvements in health-related quality of life. The effects of the PBD will be compared to a habitual diet, that includes no dietary changes. Participants in the intervention group will: * Receive weekly delivery of food boxes which include plant-based food items * Receive a daily multivitamin supplement * Receive continuous dietetic guidance * Participate in a practical cooking class to get an introduction to a PBD * Participate in three online supervisions throughout the intervention period Participants in the control group will follow the same plan for the project visits at the hospital but will be restricted to continue their habitual diet. Thus, not performing any dietary changes.

CONDITIONS

Official Title

Plant-Based Diet for Patients With Rheumatoid Arthritis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age ≥18 years
  • DAS28 score ≤3.2, and without swollen joints
  • RA diagnosis of minimum one year
  • Stable pharmacological treatment for at least four months and with no planned change in treatment within eight weeks
Not Eligible

You will not qualify if you...

  • Smokers
  • Diabetes mellitus
  • Pregnancy / planned pregnancy
  • Prednisolone treatment
  • DAS28 above 3.2
  • Current dietary habits resembling intervention diet (e.g., PBD lifestyle)
  • Food allergies and intolerances
  • Unable to understand the informed consent and study procedures

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Bispebjerg and Frederiksberg Hospital, Center for Clinical Research and Prevention

Frederiksberg, Denmark

Actively Recruiting

2

The Department of Rheumatology and Spine Diseases, Copenhagen Center for Arthritis Research (COPECARE), Rigshospitalet, Glostrup

Glostrup Municipality, Denmark

Actively Recruiting

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Research Team

N

Nikita Misella Hansen, Postdoc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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