Actively Recruiting
Plant-based Protein-rich Weight Loss Intervention in 55+ Adults With Obesity
Led by Amsterdam University of Applied Sciences · Updated on 2026-02-24
200
Participants Needed
1
Research Sites
137 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The objective of the 2EAT RCT is to investigate whether a shift towards more plant-based (≥60% with a minimum of 50%) protein intake can be achieved in an energy restricted diet for three and six months in older adults (55+) with obesity. The 2EAT researchers developed a new dietary counseling plan for six months. This includes four individual consultations, five group meetings and three 24h-recalls. In these six months, participants receive dietary counseling focused on energy restriction (-500 kcal), higher protein intake (aim towards 1.2 g/kg/d, minimum of 0.8 g/kg/d). Participants are randomly allocated either to the more plant-based diet (≥60%) or the more animal-based diet (≥60%). At the start of the intervention, participants are provided with a workbook and recipe book. Secondary objectives are to assess the effect after three and six months 2EAT dietary treatment on 1) weight loss and 2) skeletal muscle mass. Exploratory objectives are to assess the effect after three and six months 2EAT dietary treatment on 1) physical health outcomes (muscle mass and physical performance), 2) body composition, 3) metabolic blood parameters, 4) vitality and quality of life, 5) nutritional intake, 6) behavioral changes, 7) evaluate the process of the dietary treatment.
CONDITIONS
Official Title
Plant-based Protein-rich Weight Loss Intervention in 55+ Adults With Obesity
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 55 or older
- Obese with BMI >30 kg/m2 or BMI >27 kg/m2 and waist circumference >88 cm (women) or >102 cm (men)
- Living independently (not in a health facility)
- Willingness to notify the general practitioner about study participation
- Written informed consent
- Willingness to follow the study protocol
- Consent from the study physician
You will not qualify if you...
- Unable to understand the Dutch language
- Cognitive impairment with MMSE score less than 15
- Receiving total or partial parenteral nutrition (TPN)
- Alcohol or drug abuse as judged by the investigator
- Currently enrolled in a fixed rehabilitation program or other intervention studies
- Receiving palliative treatment or life expectancy of 3 months or less
- Following a 100% plant-based vegetarian or vegan diet
- Previous bariatric surgery
- Active medical treatments that interfere with this study (e.g., weight loss medication like Ozempic, systemic or immune cancer therapies)
- Physical disabilities preventing meeting general daily exercise guidelines for adults
- Planning a holiday during the study period preventing attendance at group or individual sessions for more than 3 weeks
- Diagnosed with unstable coronary heart disease, decompensated heart failure, uncontrolled hypertension or arrhythmias (e.g., NYHA class >3 heart failure)
- Diagnosed degenerative neurocognitive disorders
- Diagnosed renal failure
- COPD GOLD stage greater than 3
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hogeschool van Amsterdam
Amsterdam, South Holland, Netherlands, 1067SM
Actively Recruiting
Research Team
S
Susanne Wildemast
CONTACT
S
Sjors Verlaan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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