Actively Recruiting
Plantar Fasciitis Randomized Clinical Control Trial
Led by University of Pennsylvania · Updated on 2025-10-10
62
Participants Needed
1
Research Sites
500 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The primary aim of this clinical experiment is to compare, in terms of pain relief measured using the 10-cm visual analog scale (VAS) pain score (5-7), the clinical results of ultrasound-guided injection (USGI) versus anatomic topography-guided injection (ATGI) of corticosteroid for the treatment of proximal PF. Secondary aims will be to compare foot-related quality of life, as measured using the Foot Function Index (FFI)and the Bristol Foot Score (BFS), between the injection groups, and also to compare the pre-injection to late-term post-injection thickness of the plantar fascia as measured in the nested USGI group.
CONDITIONS
Official Title
Plantar Fasciitis Randomized Clinical Control Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pain on palpation along the proximal plantar fascia with or without radiographic evidence of a plantar calcaneal bone spur
- 18 years of age or older
- Male or non-pregnant female of any ethnicity or race
- Active, former, or non-smoker
- With or without peripheral vascular disease without lower extremity intermittent claudication or rest pain
- With or without diabetes mellitus without polyneuropathy
- With or without collagen vascular disease without lower extremity wound formation
You will not qualify if you...
- Known drug or alcohol dependence
- Chronic pain syndrome or lumbosacral radiculitis
- Neurological condition requiring analgesic, anti-seizure, or neuroleptic medications
- Peripheral vascular disease causing rest pain, intermittent claudication, or venous stasis ulceration
- Calcaneal stress fracture or presence of foreign body or tumor in affected heel on X-ray
- Pregnant females
- Known allergy to any injection therapy components
- Rupture or surgery of the plantar fascia within 5 years before participation
- Existing or prior osteomyelitis of the involved calcaneus
- Unable to consent or currently enrolled in another clinical trial
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania, United States, 19104
Actively Recruiting
Research Team
D
Donald S Malay, DPM
CONTACT
H
Hye R Kim, DPM
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
2
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