Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage in Patients with Acute Ischemic Stroke: A Prospective Observational Study

What this Trial Is About

The trial investigates acute ischemic stroke patients to explore how intraplaque hemorrhage (IPH) detected by non-contrast carotid artery MRI relates to stroke events on the same side of the body. The study aims to see if this MRI sequence can improve stroke diagnosis and identify vulnerable plaques, especially since many strokes have unclear causes. It includes both a prospective observational study with one year of follow-up and an analysis of past clinical data to better understand the prevalence of IPH in routine care. Patients with acute ischemic stroke who underwent non-contrast carotid MRI as part of their regular diagnostic process are invited to join the prospective study involving telephone follow-ups to track any recurrent strokes or transient ischemic attacks (TIAs). The study uses a simpler MRI sequence that can detect IPH reliably without contrast, making it easier to integrate into routine clinical practice. Additionally, retrospective data from previous patients who had the same MRI scan will be reviewed to complement the prospective findings. Participants will be monitored for one year to assess outcomes related to stroke recurrence and plaque vulnerability. Researchers will review MRI scans, clinical data, and follow-up information collected by phone. The main focus is on the presence of IPH at the start of the study and its association with subsequent ischemic events. This approach may help improve stroke subtype classification and better predict risk of future vascular problems.

Plaque Imaging in Routine Care to Detect Intraplaque Hemorrhage