Actively Recruiting
Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma
Led by Sun Yat-sen University · Updated on 2026-05-08
500
Participants Needed
3
Research Sites
439 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims at exploring whether plasma radiofrequency ablation at low temperature is associated with better survival outcome in localized recurrent nasopharyngeal carcinoma by conducting a randomized controlled trial of plasma radiofrequency ablation at low temperature versus electrocautery block resection at high frequency for localized recurrent nasopharyngeal carcinoma. If the hypothesis is confirmed, it is expected to provide a convenient choice for the surgical treatment of localized recurrent nasopharyngeal carcinoma.
CONDITIONS
Official Title
Plasma Radiofrequency Ablation at Low Temperature Versus Electrocautery Block Resection at High Frequency for Localized Recurrent Nasopharyngeal Carcinoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- At least 6 months disease free interval since initial radiotherapy
- Histopathological diagnosis of undifferentiated or differentiated, nonkeratinizing nasopharyngeal carcinoma
- Resectable recurrent nasopharyngeal carcinoma (rT1-3N0-3M0) with tumor confined to nasopharyngeal mucosa or specified nearby areas and at least 0.5cm from the internal carotid artery
- Cervical lymph node lesions not infiltrating cervical spine, brachial plexus, cervical muscles, or internal carotid artery
- Age between 18 and 70 years
- Signed informed consent form
You will not qualify if you...
- Karnofsky score (KPS) less than or equal to 70
- Presence of other malignant tumors
- Serious mental disease
- Uncontrolled significant heart disease or pulmonary dysfunction
- Pregnancy or breastfeeding
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, China, 510060
Actively Recruiting
2
The Fifth Affiliated Hospital of Sun Yat-sen University
Zhuhai, Guangdong, China, 519000
Actively Recruiting
3
The Nanchang Affiliated Hospital, Sun Yat-Sen University (Nanchang First Hospital)
Nanchang, Jiangxi, China
Actively Recruiting
Research Team
M
Ming-Yuan Chen, MD, PhD
CONTACT
Y
You-Ping Liu, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here