Actively Recruiting
Platelet Function After Cardiac Surgery.
Led by Insel Gruppe AG, University Hospital Bern · Updated on 2025-06-06
40
Participants Needed
1
Research Sites
81 weeks
Total Duration
On this page
Sponsors
I
Insel Gruppe AG, University Hospital Bern
Lead Sponsor
U
University Hospital, Geneva
Collaborating Sponsor
AI-Summary
What this Trial Is About
Intraoperative cell salvage is commonly used in cardiac surgery to reduce the administration of allogeneic red blood cells and thus improve the outcome for the patient. When processing the salvaged blood, however, a large part of the patient's plasma is washed out. This is a disadvantage with regard to an optimal coagulation situation after cardiac surgery. There are currently various cell saver systems on the market. According to the manufacturers, the plasma is returned to the patient in different quantities as part of the processing procedure. Thus, it can be assumed that in addition to red blood cells, platelets (part of plasma) are retransfused and contribute to an optimized coagulation. Unfortunately, there is a lack of studies in this regard in the cardiac surgery population. The investigators aim to study the performance of two different cell saver devices regarding preservation of platelet number and function.
CONDITIONS
Official Title
Platelet Function After Cardiac Surgery.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Scheduled for elective high-risk cardiac surgery with cardiopulmonary bypass
- Expected cardiopulmonary bypass time longer than 120 minutes
- Ability to provide written informed consent
You will not qualify if you...
- Use of oral or intravenous anticoagulants or antiplatelet agents before surgery, except aspirin
- Unable to understand or sign the informed consent form due to language difficulties, dementia, or mental disorders
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Department of Anesthesiology and Pain Medicine
Bern, Switzerland, 3010
Actively Recruiting
Research Team
F
Fabio Barattiero, MD
CONTACT
G
Gabor Erdoes, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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