Study of Platelet-Rich Plasma Injections From Cord Blood Combined With Penile Traction Versus Penile Traction Alone for Men With Peyronies Disease

What this Trial Is About

Researchers are evaluating the usefulness of Platelet-Rich Plasma Injections from Cord Blood CB-PRP in treating Peyronies disease, a condition involving penile curvature. This study compares patient satisfaction and other health measures between two groups those using penile traction alone and those using penile traction combined with CB-PRP injections. The main goal is to assess satisfaction using the Peyronies Disease Questionnaire PDQ at 1 and 3 months after treatment. Participants will be randomly assigned to one of two groups. One group will use a penile extender device alone, while the other will receive three CB-PRP injections every 15 days in addition to using the penile extender. This open-label study takes place at a single center and is sponsored by Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico. During the study, researchers will measure penile curvature with a goniometer during spontaneous erection and penile length in a stretched state before and after treatment at 1 and 3 months. Quality of life will also be evaluated using the Short-Form Health Survey 12 SF-12 and the Hospital Anxiety and Depression Scale HADS. Patient satisfaction will be followed for up to 6 months after enrollment, with safety and health assessments including blood counts and infection screening.

Platelet-Rich Plasma Injections From Cord Blood + Penile Traction vs. Penile Traction Alone in Patients With Peyronie's Disease. Open-label, Single-center Randomized Study