Platelet-Rich Plasma Injections From Cord Blood Penile Traction vs. Penile Traction Alone in Patients With Peyronies Disease

What this Trial Is About

Researchers are evaluating the usefulness of Platelet-Rich Plasma Injections from Cord Blood CB-PRP in treating Peyronies disease, a condition involving penile curvature. This study compares patient satisfaction and other health measures between two groups those using penile traction alone and those using penile traction combined with CB-PRP injections. The main goal is to assess satisfaction using the Peyronies Disease Questionnaire PDQ at 1 and 3 months after treatment. Participants will be randomly assigned to one of two groups. One group will use a penile extender device alone, while the other will receive three CB-PRP injections every 15 days in addition to using the penile extender. This open-label study takes place at a single center and is sponsored by Fondazione IRCCS Ca Granda, Ospedale Maggiore Policlinico. During the study, researchers will measure penile curvature with a goniometer during spontaneous erection and penile length in a stretched state before and after treatment at 1 and 3 months. Quality of life will also be evaluated using the Short-Form Health Survey 12 SF-12 and the Hospital Anxiety and Depression Scale HADS. Patient satisfaction will be followed for up to 6 months after enrollment, with safety and health assessments including blood counts and infection screening.

Platelet-Rich Plasma Injections From Cord Blood + Penile Traction vs. Penile Traction Alone in Patients With Peyronie's Disease. Open-label, Single-center Randomized Study