Actively Recruiting
Treatment of Male Infertility Using Platelet Rich Plasma Injection in Men with Failed Testicular Sperm Extraction
Led by Stanford University · Updated on 2026-01-13
10
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying the use of autologous platelet rich plasma PRP injections into the testes to improve sperm retrieval rates and in vitro fertilization IVF outcomes in infertile men who have previously had unsuccessful testicular sperm extraction TESE. This study focuses on men with nonobstructive azoospermia NOA who have already experienced negative sperm retrieval, as there are currently no alternative treatments after failed TESE. Participants will have blood drawn to prepare the PRP infusion using a centrifuge and an Arteriocyte Magellan kit. After local anesthesia, the PRP is injected into each testicle. Three months after this procedure, another TESE will be performed. If successful, the sperm obtained will be used in a new IVF cycle. During the study, participants will be monitored for sperm presence three months after the PRP injection as the primary outcome. The process includes the blood draw, PRP injection, and follow-up TESE. The study is sponsored by Stanford University and participation involves visits for treatment and evaluation within a timeframe up to the end of 2026.
CONDITIONS
Brief Title
Platelet Rich Plasma Testis Treatment for Infertile Men
Research Team
S
Satvir Basran
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